Lale Dawut
Lab. Molecular
Gerontology, NIA, NIH
(410) 558-8576
Research Experience and
Education:
August
2000 August – the present
Senior
Research Associate, Molecular Gerontology Lab., National Institute of Aging,
National Institute of Health,
January
1992 – July 2000
Post
Doctoral Research Associate, Department of Biochemistry and Biophysics,
September
1985 – December 1991
Lecturer of Forensic Science, Department of Law,
March
1984 – March 1985
Visiting Scholar, Department of Forensics,
September
1979 – June 1983
Medical Doctor Degree, Department of Medical Science,
Publications:
1. von Kobbe,
C., Harrigan, J., May, A., Opresko,
P., Dawut, L., Cheng, W., and Bohr, V.A. “
A central role for the WRN/PARP-1 complex in the poly (ADP-RIBOSYL)ation pathway after DNA damage.”
2. von Kobbe,
C., Karmakar, P., Dawut, L., Opresko, P., Zeng,
X., Brosh Jr., R.M., Hickson,
I.D. and Bohr, V.A. “Colocalization, physical
and functional interaction between Werner and Bloom syndrome proteins.” J. Biol. Chem., 277, 22035-44, 2002.
3. Thresher RJ, Vitaterna MH, Miyomoto Y, Kazantsev A, Hsu DS, Petit C, Selby CP, Dawut L, Smithies O, Takabashi JS, Sancar A (1998) “Role of mouse cryplochrome
blue-light photoreceptor in circadian photoresponses.”
Science 282, 1490-1494.
4. Nalhotra K, Kim ST, Batschauer A, Dawut L, Sancar A (1995) “Putative blue-light photoreceptors
from Arabidopsis thaliana and Sinapis alba with a
high degree of sequence homology to DNA photoyase
contain the two photolase cofactors but lack DNA
repair activity.” Biochemistry 34:
6892-6899.
5.
Poly(ADP-ribose) polymerase 1 regulates both the exonuclease and helicase
activities of the Werner syndrome protein Cayetano
von Kobbe, Jeanine A. Harrigan,
Valerie Schreiber, Patrick Stiegler Jason Piotrowski, Lale Dawut, and Vilhelm A. Bohr Nucl. Acids. Res.
2004 32: 4003-4014.
Language Skills: